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Research · Chicago

What research is done in Chicago?

Papers authored at Chicago's institutions — Northwestern University, University of Chicago, University of Illinois Chicago — with the Prism stance layer.

Summary

Research is one of Chicago’s clearest assets. The partial data counts 26741 papers, led by Northwestern University at 9127 and the University of Chicago at 8900; machine learning, women’s health and children’s health stand out as opportunity areas.

WATCH Watch whether strong medical and machine-learning work translates into companies and clinical progress.
Research outlook for Chicago

What the papers — written in the city and about it — point to, split by the Prism stance layer: work that reads promising versus work that flags problems or urges caution.

Opportunities the research points to
Machine Learning · 206Women's Health · 203Children's Health · 180Healthcare · 171Breast Cancer · 170Neuroscience · 165Mental Health · 133Artificial Intelligence · 110Deep Learning · 99COVID-19 · 96Men's Health · 90Cancer · 90
Concerns the research raises
Healthcare · 281Children's Health · 199Women's Health · 196COVID-19 · 141Mental Health · 135Research · 125Education · 101Artificial Intelligence · 87Patient Care · 84Patients' Health · 80Men's Health · 59Public Health · 51

counts = papers carrying the theme · concerns merge cautionary, critical and problem-identifying work

Institutions
Orientation
Output by year (sample)
2026: 69620172026696
Opportunities (promising + breakthrough)
Machine Learning · 201Women's Health · 198Children's Health · 180Healthcare · 171Breast Cancer · 170Neuroscience · 165Mental Health · 133Artificial Intelligence · 110Deep Learning · 99COVID-19 · 96Men's Health · 90Cancer · 90
Cautions (cautionary + critical)
Healthcare · 59Children's Health · 55Women's Health · 54COVID-19 · 42Mental Health · 34Education · 29Patient Care · 27Patients' Health · 25Research · 24Artificial Intelligence · 23Men's Health · 22Women's Rights · 21
Problems flagged
Healthcare · 216Children's Health · 144Women's Health · 142Research · 101Mental Health · 101COVID-19 · 94Education · 68Artificial Intelligence · 64Patient Care · 57Patients' Health · 55Public Health · 51Men's Health · 37
Top research topics
Cancer Genomics and Diagnostics · 264Cancer Immunotherapy and Biomarkers · 257Epigenetics and DNA Methylation · 230CAR-T cell therapy research · 210Innovations in Medical Education · 206Health disparities and outcomes · 201Stellar, planetary, and galactic studies · 201Dementia and Cognitive Impairment Research · 200RNA modifications and cancer · 194Gamma-ray bursts and supernovae · 191Galaxies: Formation, Evolution, Phenomena · 186Neural dynamics and brain function · 185
Most-cited work
PaperYearCitedOrientation
One size fits all? What counts as quality practice in (reflexive) thematic analysis?20207540Problem Identifying
performance: An R Package for Assessment, Comparison and Testing of Statistical Models20214792Descriptive
AASLD guidelines for the treatment of hepatocellular carcinoma20174115Critical
Tisagenlecleucel in Adult Relapsed or Refractory Diffuse Large B-Cell Lymphoma20183936Promising
Clinical Practice Guidelines for the Prevention and Management of Pain, Agitation/Sedation, Delirium…20183709Problem Identifying
The 5th edition of the World Health Organization Classification of Haematolymphoid Tumours: Lymphoid Neoplasms20223466Descriptive
An epigenetic biomarker of aging for lifespan and healthspan20183364Breakthrough
Dapagliflozin in Heart Failure with Mildly Reduced or Preserved Ejection Fraction20222473Promising
DNA methylation GrimAge strongly predicts lifespan and healthspan20192454Breakthrough
CASTp 3.0: computed atlas of surface topography of proteins20182318Breakthrough
Beyond fossil fuel–driven nitrogen transformations20182298Problem Identifying
A Survey on Evaluation of Large Language Models20242212Problem Identifying
Nature and mental health: An ecosystem service perspective20191768Problem Identifying
The Impact of COVID-19 on Gender Equality20201711Problem Identifying
Deep Back-Projection Networks for Super-Resolution20181611Breakthrough

figures marked ≈ are scaled estimates from a partial sample · Prism stance layer over 2017+ papers

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